Society / May 2, 2026

The Fifth Circuit Seeks to Unilaterally Reimpose an Outdated Abortion Pill Protocol

What comes next is shifting terrain. The drug manufacturer has asked the Supreme Court to intervene, but the Food and Drug Administration could also step in.

Rachel Rebouché
Telehealth abortion—in which a provider, patient, and pharmacy all interact online and pills are mailed to patients—accounts for more than a quarter of all abortions.(Kayla Bartkowski / The Boston Globe via Getty Images)

Update: On Monday morning, the US Supreme Court restored access to abortion medication via telehealth. The order, written by Justice Samuel Alito, extended a stay on the Fifth Circuit’s ruling for one week “while both sides respond and the court more fully considers the issue,” the Associated Press reports.

On Friday night, the US Court of Appeals for the Fifth Circuit issued an 18-page order that winds back the clock to 2016. The order reimposes a restriction on mifepristone, the first part of a two-drug regimen to end a pregnancy, that requires patients pick up the pill at a healthcare facility—in effect, banning the use of telehealth for medication abortion nationwide, at least temporarily.

Telehealth abortion—in which a provider, patient, and pharmacy all interact online and pills are mailed to patients—accounts for more than a quarter of all abortions and has been growing in popularity since the Covid-19 pandemic and the US Supreme Court overturned Roe v. Wade. Since the Dobbs v. Jackson Women’s Health Organization decision in 2022, patients in states with abortion bans have been receiving the medication by mail from providers in states where abortion remains legal, who operate according to their own state’s laws. But as telehealth abortion and medication abortions broadly became more widely used, anti-abortion activists have deployed a variety of tactics to threaten the legality of and access to the medication. Louisiana v. FDA, the lawsuit before the Fifth Circuit, marked the latest attempt, but certainly not the first or last, to challenge telehealth abortion.

Louisiana brought the lawsuit against the Food and Drug Administration in October of last year, arguing that the agency acted unlawfully when, practically in 2021 and officially in 2023, it lifted a restriction on mifepristone that required patients to pick up the medication at a clinic, although patients did not have to take mifepristone in a provider’s presence. The rule changed in the wake of litigation during Covid-19 and on the back of extensive research establishing the safety of telehealth for medication abortion.

Prior to Louisiana’s lawsuit, a group of anti-abortion doctors pursued the same outcome, in addition to asking the FDA to remove its 2000 approval of the drug. Those doctors, suing as the Alliance for Hippocratic Medicine, lost before the Supreme Court in 2024; a unanimous court held that they did not have standing, or could not prove an actual injury from the FDA’s rule. Anticipating the Supreme Court’s decision, other states—Missouri, Kansas, and Idaho—intervened in the case to assert their states’ standing. These states mirrored the Alliance’s legal strategy but also argued to the district court that out-of-state providers mailing abortion pills to residents of their states threatened state lawmakers’ ability to enforce their abortion bans. Texas and Florida took the same course in lodging a separate case.

Louisiana filed their own lawsuit attacking only the decision to lift the in-person requirement. The FDA requested that the district court in Louisiana hold the case until the agency “reconsidered the restrictions on mifepristone based on all the evidence.” Health and Human Services Secretary Robert F. Kennedy Jr. announced a review last fall in response to letters by Republicans pressuring the HHS for the rule’s reinstatement and following the release of a widely discredited paper, published by an anti-abortion organization, calling into question mifepristone’s safety record.

Louisiana, not to be deterred, appealed the district court’s decision to the Fifth Circuit, which issued its decision on Friday. That ruling orders that the in-person pickup rule be put back in place, meaning that patients nationwide must pick up the medication from a clinic or hospital. The Fifth Circuit brushed aside the arguments made by the FDA about its ongoing review—which, to be clear, is unnecessary given the long-standing safety track record of mifepristone. And it discounted the judgments of other federal district courts, such as one issued last October, that found the current restrictions on mifepristone, before and after the 2023 FDA decision, to be unnecessarily burdensome and unlawful.

So, in the face of an agency request, contrary federal court decisions, and a strong evidentiary record of safety and efficacy, the Fifth Circuit seeks to unilaterally reimpose a drug restriction that will affect thousands of Americans.

What comes next is shifting terrain. The drug manufacturer has asked the Supreme Court to intervene to keep the status quo while the case proceeds through the courts. The Supreme Court previously issued a stay during the original litigation, when the Fifth Circuit first sought to change FDA regulations. If the justices agree with the manufacturer, telehealth for medication abortion will continue as it has for the last five years. If not, telehealth providers will face a changing legal landscape.

Repro Nation

Monthly. A collection of stories, analysis, and resources on the global struggle for reproductive freedom.
By signing up, you confirm that you are over the age of 16 and agree to receive occasional promotional offers for programs that support The Nation’s journalism. You may unsubscribe or adjust your preferences at any time. You can read our Privacy Policy here.

For one, the Fifth Circuit suggests that its holding is immediate—in other words, the old rule applies now. But that says nothing of the pills that are presently in providers’ or distributors’ possession, acquired for the purpose of telehealth before the court’s decision. Or patients who have appointments for telehealth made before Friday’s ruling. For another, the FDA has enforcement discretion, which means that the agency could announce that it will not pursue any actions against people who need time to adjust to a new regime.

Pausing now is important, because the Fifth Circuit only seems to care about pills’ transit into states with bans, which Louisiana and other states claim impedes their ability to enforce their abortion bans. Suspend for a moment the continuing problem of standing—the claim that a state itself is injured from a rule that allows telehealth across the country—the Fifth Court paid no attention to the fact that everyone in every state would be affected by a disruption in service in weighing the costs of its order.

Moreover, the FDA deals largely with drug manufacturers and distributors, not with providers. The normal process for reversing a drug regulation requires study and evidence; though ignored by the Fifth Circuit, all the data points to mifepristone’s safety generally as well as when delivered through telehealth. Friday’s judgment short-circuits whatever process comes next, without any direction for the providers or pharmacies potentially caught in the crosshairs.

Whatever the Supreme Court decides, no one should expect pills to stop reaching patients. International abortion pill access will continue to exist. And the second part of the two-drug regimen, misoprostol, can end a pregnancy by itself and is not subject to the Fifth Circuit’s decision.

And no matter what comes next, it’s worth remembering that the Louisiana case is one strand of a multipronged attack on mifepristone. Here, the Fifth Circuit has focused on a dubious claim about states’ being able to enforce their laws. In this and other attacks, states repeat bogus allegations that telehealth for medication abortion is ripe for misuse and results in patients’ physical and mental harm. These arguments are all designed to end abortion across the country. But if we have learned anything from the Dobbs decision and every attempt to ban abortion since then, people will not stop having abortions, and that includes accessing abortion medication by mail.

Your support makes stories like this possible

From illegal war on Iran to an inhumane fuel blockade of Cuba, from AI weapons to crypto corruption, this is a time of staggering chaos, cruelty, and violence. 

Unlike other publications that parrot the views of authoritarians, billionaires, and corporations, The Nation publishes stories that hold the powerful to account and center the communities too often denied a voice in the national media—stories like the one you’ve just read.

Each day, our journalism cuts through lies and distortions, contextualizes the developments reshaping politics around the globe, and advances progressive ideas that oxygenate our movements and instigate change in the halls of power. 

This independent journalism is only possible with the support of our readers. If you want to see more urgent coverage like this, please donate to The Nation today.

Rachel Rebouché

Rachel Rebouché is the G. Rollie White Chair in Law and professor of law at the University of Texas at Austin School of Law

More from The Nation

Jesse at Valley Forge Military Academy.

How the Military Mindset Has Crushed Our Country’s Men How the Military Mindset Has Crushed Our Country’s Men

I talked to soldiers and ROTC students about the kind of masculinity the military encourages. Its ripple effects on mental health are dire.

Jasper Craven

What the Dissents in the Mifepristone Case Tell Us About What’s to Come

What the Dissents in the Mifepristone Case Tell Us About What’s to Come What the Dissents in the Mifepristone Case Tell Us About What’s to Come

Justice Alito called the Supreme Court’s order “unreasoned” and “remarkable,” while feigning ignorance over the decades of research pointing to mifepristone’s safety.

Michele Goodwin

President Donald Trump holds a cross given to him by Archbishop Elpidophoros of the Greek Orthodox Archdiocese of America.

The Hypocrisy of Trump’s 9-Hour Prayer Festival The Hypocrisy of Trump’s 9-Hour Prayer Festival

The claim that the founders meant America to be a Christian nation isn’t just bad history—it’s a declaration of war by the religious right.

Chris Lehmann

Payback master: FBI Director Kash Patel in testimony before the Senate Appropriations Committee this week.

Government by Payback Squad Government by Payback Squad

The Trump White House has weaponized all the arms of federal law enforcement to intimidate its political enemies and critics, undermining the rule of law and democracy.

David Faris

AI Is Incapable of Poetry

AI Is Incapable of Poetry AI Is Incapable of Poetry

It’s incapable of producing anything creative that isn’t dreck.

Column / Katha Pollitt

A video still of Bill Gates walking past reporters after being hit by a cream pie in Brussels, Belgium, 2000.

Is Antitrust Enough? Is Antitrust Enough?

Tim Wu’s Age of Extraction lays out an antitrust strategy for fighting platform capitalism. But does the challenge posed by Big Tech require a new playbook?

Books & the Arts / Michael Eby